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We convene this important international conference six decades since
the first report that a chemical can be mutagenic; five decades since
the double-helical structure of DNA was revealed; and four decades since
the discovery of excision-repair, which removes pre-mutagenic lesions
from DNA to prevent mutagenesis.
The broad subject of the 9th ICEM transcends national boundaries and
is timely for all peoples of the world. In recent years, we have learned
a great deal about the threats to human health from genotoxic chemicals
and radiations in our environment. We also have learned of many inherited
and acquired genetic alterations that predispose individuals to cancer,
premature aging, and other diseases. The sequencing of the entire human
genome (as well as that of many other organisms), along with the development
of powerful new technologies, promises to yield even more impressive
advances in the coming decade. It should certainly become possible to
identify and reduce most of the principal environmental hazards that
threaten our health and that of the planet. These hazards include not
only genotoxins but also infectious agents and chemicals that adversely
effect important cellular processes.
To highlight these issues and to explore solutions to these global
threats to our collective health, the 9th ICEM will offer many symposia
and plenary lectures from the world leaders in environmental mutagenesis
and related fields. Broadly, speakers will address how environmental
contaminants can damage the genome, how such damage may be repaired
or else processed into mutations, and how the resulting mutations may
lead to disease. Symposia at the cutting-edge of basic and applied research
will present details of new technologies in molecular biology and biomedical
research as they apply to the global problem of maintaining genomic
integrity and human health. There will be opportunities for researchers
from all countries to present their most recent research in poster and
platform sessions. We will also include relevant workshops and special
programs for students, who will be the scientists and leaders of the
future. The venue for the conference will be the Hyatt Regency San Francisco
Hotel at the Embarcadero waterfront in the heart of the lovely city
of San Francisco, California. We enthusiastically look forward to welcoming
you to the 9th ICEM in September 2005.
Philip C. Hanawalt
President/Chair of the Organizing Committee
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