2004 EMS Agenda (revised June 1, 2004)
Dates
Saturday, October 2
| 8:00 AM - 10:30 AM | EMS Executive Board Meeting | |
| 1:00 PM - 5:00 PM | EMS Council Meeting | |
| 1:30 PM - 4:40 PM | Forum: The SHE Cell Transformation Assay Is Back! Should It Be?Organizer: Aisar Atrakchi, U.S. FDA |
|
| 1:30 PM - 1:35 PM | Introduction Aisar Atrakchi, U.S. FDA |
|
| 1:35 PM - 2:10 PM | SHE: A Cell Transformation Assay, Historical Perspectives, Techniques
and Application James Klaunig, Indiana University School of Medicine |
|
| 2:10 PM - 2:45 PM | Performance
of this In Vitro Model for Predicting Rodent Carcinogenicity Dr. Brian Myhr, Covance Laboratories |
|
| 2:45 PM - 3: 00 PM Break | ||
| 3:00 PM - 3:35 PM | The SHE Cell Transformation Assay - A Pharmaceutical
Industry Perspective James S. Harvey, GlaxoSmithKline |
|
| 3:35 PM - 4:10 PM | The Role of the SHE Cell Transformation Assay in Drug
Development David Jacobson-Kram, U.S. FDA |
|
| 4:10 PM - 4:40 PM | Panel Discussion and Open Forum | |
| 5:00 PM - 8:00 PM | Student Poster Session and Welcoming Reception |
|
Sunday, October 3
| 7:00 AM - 8:30 AM |
Breakfast Meetings2005 Program Committee (first meeting)Molecular Epidemiology Special Interest Group Transgenic & In Vivo Mutagenesis Special Interest Group |
|
| 8:30 AM - 12:00 PM |
Human Variation and Cancer Susceptibility SymposiumChairpersons: Marianne Berwick, University of New Mexico and David Hunter, Harvard School of Public Health |
|
| 8:30 AM - 8:40 AM |
Introduction | |
| 8:40 AM - 9:10 AM | DNA Repair Capacity and Cancer
Marianne Berwick, University of New Mexico |
|
| 9:10 AM - 9:40 AM | Radical Causes of Human Cancer: Inflammation, Nitric
Oxide and p53 Curtis C. Harris, National Cancer Institute |
|
| 9:40 AM - 10:10 AM | Haplotypes and Cancer Risk David Hunter, Harvard School of Public Health |
|
| 10:10 AM - 10:30 AM | Break | |
| 10:30 AM - 11:00 AM | DNA Sequence Variation and Linkage Disequilibrium:
Roles in Cancer Etiology Debbie Nickerson, University of Washington |
|
| 11:00 AM - 11:30 AM | Genetic and Environmental Modifiers of Penetrance
in
BRCA1 and BRCA2 Carriers Timothy R. Rebbeck, University of Pennsylvania |
|
| 11:30 AM - 12:00 PM | The Role of Methylation in Lung Cancer Etiology Steve Belinsky, Lovelace Respiratory Research Institute |
|
| 8:30 AM - 12:00 PM | Platform Session 1: Responses to Environmental AgentsChairpersons: Priscilla K. Cooper, Lawrence Berkeley National Laboratory and Joann B. Sweasy, Yale University School of Medicine |
|
| 1:00 PM - 4:30 PM | Unusual Mechanisms of Mutation Symposium Chairpersons: Paul Doetsch, Emory University and Patricia Foster, Indiana
University |
|
| 1:00 PM - 1:10 PM | Introduction | |
| 1:10 PM - 1:40 PM | Stress-Induced Mutagenesis in Bacteria Patricia Foster, Indiana University |
|
| 1:40 PM - 2:10 PM | Transcriptional Mutagenesis in Bacteria and
Mammals Paul Doetsch, Emory University School of Medicine |
|
| 2:10 PM - 2:40 PM | Mutagenesis via Mistranslation M. Zafri Humayun, University of Medicine and Dentistry of New Jersey |
|
| 2:40 PM - 3:10 PM | AID-Mediated Somatic Hypermutation Matthew Scharff, Albert Einstein College of Medicine |
|
| 3:10 PM - 3:30 PM | Break | |
| 3:30 PM - 4:00 PM | Surveillance Mechanisms Discriminating Between Functional and Mutant Transcripts Miles Wilkinson, University of Texas, MD Anderson Cancer Center |
|
| 4:00 PM - 4:30 PM | New Mechanisms for Mitochondrial Mutations and
Human
Disease Michio Hirano, Columbia University |
|
| 1:00 PM - 4:30 PM | Germ and Stem Cell Mutagenesis Symposium Chairpersons: Sheila Galloway, |
|
| 1:00 PM - 1:10 PM | Introduction | |
| 1:10 PM - 1:40 PM | Asymmetric Cell Kinetics and Control of Growth
and Mutation
in Stem Cells James Sherley, Massachusetts Institute of Technology |
|
| 1:40 PM - 2:10 PM | Mutation Rates and Apoptosis Control in Cultured
Stem
Cells Peter J. Stambrook, University of Cincinnati |
|
| 2:10 PM - 2:40 PM | Selection in the Male Germ Line and the Paternal
Age
Effect on Human Mutation Andrew Wilkie, University of Oxford |
|
| 2:40 PM - 3:10 PM | Genotyping Individual Germ Cells Norman Arnheim, University of Southern California |
|
| 3:10 PM - 3:30 PM | Break | |
| 3:30 PM - 4:00 PM | Estimation of Human Mutation Rate and Comparisons
with
the Mouse Genome Alexey Kondrashov, National Center for Biotechnology Information |
|
| 4:00 PM - 4:30 PM | To Be Announced | |
| 4:30 PM - 5:30 PM | Keynote Lecture - Philip A. Sharp, Massachusetts Institute of
Technology |
|
| 5:30 PM - 7:30 PM |
Exhibits and Poster Session 1 |
|
Monday, October 4
| 7:00 AM - 8:30 AM | Breakfast Meetings Exhibitor’s Breakfast |
|
| 8:30 AM - 12:00 PM | Recombination and the Maintenance of Genome Stability SymposiumChairpersons: Bevin Engelward, Massachusetts Institute of Technology and John A. Tainer, The Scripps Research Institute |
|
| 8:30 AM - 8:40 AM | Introduction | |
| 8:40 AM - 9:10 AM | Structural Aspects of Recombination Repair John A. Tanier, The Scripps Research Institute |
|
| 9:10 AM - 9:40 AM | Mouse Models for Measuring In Vivo DNA Recombination Bevin P. Engelward, Massachusetts Institute of Technology |
|
| 9:40 AM - 10:10 AM | Targeting Recombination Events
in Yeast Michael A. Resnick, National Institute of Environmental Health Sciences |
|
| 10:10 AM - 10:30 AM | Break | |
| 10:30 AM - 11:00 AM | Molecular Mechanisms of Recombination Steven C. Kowalczykowski, University of California, Davis |
|
| 11:00 AM - 11:30 AM | The Interface Between End Joining and Homologous
Recombination Jac Nickoloff, University of New Mexico |
|
| 11:30 AM - 12:00 PM | To Be Announced | |
| 8:30 AM - 12:00 PM | Platform Session 2: Mechanisms of MutationChairpersons: Ronald D. Snyder, Schering-Plough Research Institute and Rosalie K. Elespuru, U.S. FDA |
|
| 1:00 PM - 4:30 PM | Metals, Mutagenesis and Cancer SymposiumChairpersons: Toby G. Rossman, New York University and Kathleen Dixon, University of Cincinnati |
|
| 1:00 PM - 1:10 PM | Introduction | |
| 1:10 PM - 1:40 PM | Arsenic as a Co-Carcinogen Toby G. Rossman, New York University |
|
| 1:40 PM - 2:10 PM | Chromium - Mechanisms of Mutagenesis Kathleen Dixon, University of Cincinnati |
|
| 2:10 PM - 2:40 PM | Nickel-Induced Chromatin Damage Kazimierz S. Kasprzak, National Cancer Institute |
|
| 2:40 PM - 3:10 PM | Iron Overload as a Cause of Cancer Xi Huang, New York University |
|
| 3:10 PM - 3:30 PM | Break | |
| 3:30 PM - 4:00 PM | Biomarkers of Susceptibility and Effect of Arsenic
Carcinogenesis
in Human Population Habibul Ahsan, Columbia University |
|
| 4:00 PM - 4:30 PM | Inhibition of Inducible Gene Expression by Chromium Alvaro Puga, University of Cincinnati |
|
| 1:00 PM - 4:30 PM | Microbes, Mutation and Malignancy SymposiumChairpersons: David Schauer, Massachusetts Institute of Technology and Lorne Hofseth, University of South Carolina |
|
| 1:00 PM - 1:10 PM | Introduction | |
| 1:10 PM - 1:40 PM | Colonic Infection and Cancer Susceptibility David Schauer, Massachusetts Institute of Technology |
|
| 1:40 PM - 2:10 PM | Induction of a Mutator Phenotype in Inflamed Tissues Lorne Hofseth, University of South Carolina |
|
| 2:10 PM - 2:40 PM | Carcinogenicity of Helicobacter Pylori Infection Pelayo Correa, Louisiana State University |
|
| 2:40 PM - 3:10 PM | Lessons Learned from Molecular Profiling of Human
Hepatocellular
Cancer Xin Wei Wang, National Cancer Institute |
|
| 3:10 PM - 3:30 PM | Break | |
| 3:30 PM - 4:00 PM | Induction of Genetic Instability by Human Papillomavirus
Oncoproteins Denise Galloway, Fred Hutchinson Cancer Research Center |
|
| 4:00 PM - 4:30 PM | To Be Announced | |
| 4:30 PM - 5:30 PM | Keynote Lecture - David Botstein, Princeton
University |
|
| 5:30 PM - 7:30 PM | Exhibits and Poster Session 2 |
|
Tuesday, October 5
| 7:00 AM - 8:30 AM | Breakfast Meetings EMS Executive Board Hollaender
Committee Public Relations and Communications Committee |
|
| 8:30 AM - 9:30 AM | Keynote Lecture - Elizabeth Blackburn, |
|
9:30 AM - 12:30 PM |
Exhibits and Poster Session 3 |
|
| 12:30 PM - 5:30 PM | Free Afternoon | |
| 5:30 PM - 7:00 PM | Business Meeting |
|
| 7:00 PM - 10:00 PM | Banquet and EMS Awards |
|
Wednesday, October 6
| 7:00 AM - 8:30 AM | Breakfast Meetings 2005 Program Committee |
|
| 8:30 AM - 12:00 PM | Multiple Roles for DNA Mismatch Repair SymposiumChairpersons: Thomas Kunkel, National Institute of Environmental Health Sciences and Margaret Hsieh, National Institute of Diabetes and Digestive and Kidney Diseases |
|
| 8:30 AM - 8:40 AM | Introduction | |
| 8:40 AM - 9:10 AM | Mismatch Repair Role in DNA Damage Responses Baskaran Rajasekaran, University of Pittsburgh |
|
| 9:10 AM - 9:40 AM | Mismatch Repair and Mutagenesis Due to Oxidative
Stress Margherita Bignami, Istituto Superiore di Sanit88 |
|
| 9:40 AM - 10:10 AM | Functions of Mismatch Repair Proteins in Meiosis Rhona H. Borts, University of Leicester |
|
| 10:10 AM - 10:30 AM | Break | |
| 10:30 AM - 11:00 AM | Mouse Models of Mismatch Repair Winfried Edelmann, Albert Einstein College of Medicine |
|
| 11:00 AM - 11:30 AM | Studies of the Early Steps in Mismatch Repair John B. Hays, Oregon State University |
|
| 11:30 AM - 12:00 PM | The Structural Biology of Mismatch Repair Wei Yang, National Institute of Diabetes and Digestive and Kidney Diseases |
|
| 8:30 AM - 12:00 PM | Platform Session 3: Exposure, Detection and ToxicityChairpersons: David DeMarini, U.S. EPA and Carol Yauk, Health Canada |
|
| 1:00 PM - 4:30 PM | DNA Helicases, Mutation, Cancer and Aging SymposiumChairpersons: Raymond Monnat, University of Washington and Lawrence A. Loeb, University of Washington |
|
| 1:00 PM - 1:10 PM | Introduction | |
| 1:10 PM - 1:40 PM | Human Diseases with Early Aging Are Defective
in DNA
Repair Vilhelm Bohr, National Institute on Aging |
|
| 1:40 PM - 2:10 PM | Interactions of Bypass Polymerases, p53 and Recombination
in Maintaining Genome Integrity James Cleaver, University of California, San Francisco |
|
| 2:10 PM - 2:40 PM | Mutagenesis, Genetic Instability
and Clonal Evolution in
Human Cell Lineages Barry A. Finette, University of Vermont |
|
| 2:40 PM - 3:10 PM | Werner Syndrome, Polymorphisms
and Cancer Lawrence A. Loeb, University of Washington |
|
| 3:10 PM - 3:30 PM | Break | |
| 3:30 PM - 4:00 PM | Werner Syndrome Protein Function and Disease
Pathogenesis Raymond J. Monnat, University of Washington |
|
| 4:00 PM - 4:30 PM | Loss of Genomic Integrity in Early Carcinogenesis Thea Tlsty, University of California, San Francisco |
|
| 1:00 PM - 4:30 PM | Mitochondria at the Crossroads of Life and Death Decisions SymposiumChairpersons: Susan LeDoux, University of Alabama, Mobile and Bennett Van Houten, National Institute of Environmental Health Sciences |
|
| 1:00 PM - 1:10 PM | Introduction | |
| 1:10 PM - 1:40 PM | Targeting DNA Repair Enzymes to the Mitochondria Susan LeDoux, University of Alabama, Mobile |
|
| 1:40 PM - 2:10 PM | Consequences of Iron-Mediated Mitochondrial
DNA Damage Bennett Van Houten, National Institute of Environmental Health Sciences |
|
| 2:10 PM - 2:40 PM | Molecular Genetics of Human Mitochondrial Respiratory
Chain Defects Eric A. Shoubridge, McGill University |
|
| 2:40 PM - 3:10 PM | Mitochondrial Uptake of AP-Endonuclease - A
Base
Excision Repair Enzyme Sankar Mitra, University of Texas, Galveston |
|
| 3:10 PM - 3:30 PM | Break | |
| 3:30 PM - 4:00 PM | Consequences of Mutations in DNA Polymerase
Gamma William C. Copeland, National Institute of Environmental Health Sciences |
|
| 4:00 PM - 4:30 PM | p53 Mediated Apoptosis Through Direct Interactions
with
the Mitochondria Ute Moll, State University of New York at Stony Brook |
|
| 4:30 PM - 5:30 PM | Keynote Lecture-Douglas Lauffenburger, |
|
| 5:30 PM - 6:30 PM | EMS Council Meeting | |
