EMS 2011 Annual Meeting

Sunday, October 16
7:00 AM–5:00 PM
	Registration	Inscription
7:00 AM–5:00 PM
	Speaker Ready Room Open	Inscription 2
7:00 AM–8:30 AM
	Breakfast Meetings
	Breakfast Pick-Up for Meetings (Ticket Required—Breakfast Available at 6:45 AM)	Net Café
	Applied Genetic Toxicology Special Interest Group Leaders: Krista L. Dobo, Pfizer Global R&D and Patricia A. Escobar, Boehringer Ingelheim Pharmaceuticals	Fontaine F
	Environmental Genetic Toxicology Special Interest Group Leaders: Christopher M. Somers, University of Regina and Carol D. Swartz, Integrated Laboratory Systems	Fontaine G
	Transgenic and In Vivo Mutagenesis Special Interest Group Leaders: Mugimane G. Manjanatha and Nan Mei, National Center for Toxicological Research, U.S. FDA	Fontaine H
8:30 AM–9:30 AM
	Plenary Lecture 1 (PL1) The Cancer Epigenome Chairperson: Janet E. Baulch, University of Maryland, Baltimore Lecturer: Peter A. Jones, University of Southern California, Norris Comprehensive Cancer Center	Outremont
9:45 AM–12:15 PM
	Symposium 1 Epigenetics: DNA Modifications and Repair Chairpersons: Alfonso Bellacosa, Fox Chase Cancer Center and Jacquetta M. Trasler, McGill University Organized by DNA Repair and Mutagenic Mechanisms Special Interest Group and Epigenetics Special Interest Group Underlined author indicates presenter.	Mont-Royal
9:45 AM–10:15 AM	DNA Methylation in Mammalian Development Jacquetta M. Trasler, McGill University
10:15 AM–10:45 AM	Role of 5-hydroxymethylcytosine in Reprogramming the Paternal Genome in the Zygote Piroska E. Szabó, Beckman Research Institute, City of Hope
10:45 AM–11:00 AM	Break
11:00 AM–11:30 AM	Active DNA Demethylation by Thymine DNA Glycosylases Alfonso Bellacosa, Fox Chase Cancer Center
11:30 AM–11:45 AM	Prenatal Exposures to Environmental Pollutants and Epigenetics in Children Holland N, Yosefi P, Aguilar R, Quach H, Huen K, Bradman A, Venkat S, Barcellos L, Eskenazi B. University of California, Berkeley, Berkeley, CA, United States
11:45 AM–12:00 NOON	Genomic and Epigenomic Alterations in Cells Exhibiting Radiation-Induced Genomic Instability Ding D, Aypar U, Tiper I, Goetz W, Baulch JE. University of Maryland, Baltimore, MD, United States
12:00 NOON–12:15 PM	Discussion

9:45 AM–12:15 PM
	Symposium 2 Application of Toxicogenomics in Reulatory Decision-Making Chairpersons: Guosheng Chen and Kathy Hughes, Health Canada Organized by Health Canada	Outremont
9:45 AM–9:55 AM	Challenges to the Use of Emerging Technologies in Regulatory Risk Assessment Kathy Hughes, Health Canada
9:55 AM–10:20 AM	Application of Toxicogenomics in Health Risk Assessment Michael D. Waters, Integrated Laboratory Systems, Inc.
10:20 AM–10:40 AM	Comparison of Transcriptional Benchmark Doses to Traditional Cancer and Non-Cancer Endpoints for Benzo(a)pyrene Carole L. Yauk, Health Canada Genomics Working Group
10:40 AM–11:00 AM	Opportunities for Integrating Toxicogenomic Approaches for Regulatory Decision-Making Elaine M. Faustman, University of Washington
11:00 AM–11:15 AM	Break
11:15 AM–11:35 AM	An Approach to Using Toxicogenomic Data in Risk Assessment: Dibutyl Phthalate Case Study Susan Y. Euling, U.S. Environmental Protection Agency
11:35 AM–11:55 AM	Integration of Genomic Biomarkers in Cancer Risk Assessment Paradigm Jiri Aubrecht, Pfizer Inc.
11:55 AM–12:15 PM	Practical Considerations for the Application of Toxicogenomics to Risk Assessment: Early Experience, Current Drivers, and a Path Forward Darrell R. Boverhof, The Dow Chemical Company

12:00 NOON–4:00 PM
	Access to Exhibit Hall to Affix Posters	Fontaine B
12:15 PM–2:00 PM
	Lunch on your own
12:30 PM–1:45 PM
	Student and New Investigator Brunch (Advance Registration Required)	Fontaine F
2:00 PM–4:30 PM
	Symposium 3 Etiology of Autism: Genetics, Epigenetics, and the Environment Chairpersons: Janet E. Baulch, University of Maryland, Baltimore and Barbara S. Shane, Barbara Shane Consulting Organized by Epigenetics Special Interest Group Contributing Sponsor: March of Dimes Birth Defects Foundation Supported in part by: Autism Speaks	Mont-Royal
2:00 PM–2:30 PM	Overview of the Etiology of Autism Alycia Halladay, Autism Speaks
2:30 PM–3:00 PM	Etiology of Autism: A Role for Epigenetics? Rosanna Weksburg, University of Toronto
3:00 PM–3:15 PM	Break
3:15 PM–3:45 PM	Genomic Rearrangements in Autism: The Contribution of Copy Number Loss and Gain to the Etiology of Autism Spectrum Disorders Simon G. Gregory, Duke University
3:45 PM–4:15 PM	The Epigenetic Interface of Genetic and Environmental Risk Factors in the Etiology of Autism Janine LaSalle, University of California, Davis School of Medicine
4:15 PM–4:30 PM	Discussion

2:00 PM–4:30 PM
	Symposium 4 Genotoxic Impurities: The Current Environment and Future Possibilities Chairpersons: Michelle Kenyon, Pfizer Inc. and Laura L. Custer, Bristol-Myers Squibb Organized by the Applied Genetic Toxicology Special Interest Group	Outremont
2:00 PM–2:30 PM	Mutagenic Impurities: Introduction to the Current Environment and On-Going Initiatives David De Antonis, Pfizer Inc.
2:30 PM–3:00 PM	Case Study: Illustrating Validation of In Silico Prediction of Chemicals for Mutagenicity and Calculation of Compound-Specific Threshold of Toxicological Concern (TTC) Vijay Reddy, Merck Research Laboratories
3:00 PM–3:15 PM	Break
3:15 PM–3:45 PM	Dose-Response Relations: The Impact of Non-Linearity Melanie Guerard, F. Hoffmann-La Roche Ltd.
3:45 PM–4:15 PM	Application of the In Vivo Pig-a Mutagenicity Assay for Assessing Dose Response Relationships Stephen D. Dertinger, Litron Laboratories
4:15 PM–4:30 PM	Discussion

4:30 PM–6:30 PM
	Poster Session 1 and Exhibits Odd Numbered Abstracts Attended	Fontaine B
6:30 PM
	Committee Meetings
	2012 Program Committee Meeting (First Meeting)	Longueuil
	Membership and Professional Development Committee Meeting	Pointe Aux Trembles
	Public Relations and Communications Committee Meeting	Jacques Cartier
	Publication Policy Committee Meeting	Fundy
7:30 PM
	Committee Meetings
	Special Interest Group Leaders	Pointe Aux Trembles