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New Technologies Special Interest Group

Breakfast Meeting Agenda

Monday, October 26, 2009

7:00 AM–8:30 AM

Breakfast Meeting

New Technologies Special Interest Group

Leaders: Brinda Mahadevan, Schering Plough Research Institute and Patricia A. Escobar, Boehringer-Ingelheim Pharmaceuticals

Mini-Symposium: “Genetic Toxicity of Oligonucleotide Therapeutics”

7:00 AM–7:15 AM

Breakfast
Discussion on general activities of the SIG and webpage development
Symposium/workshop topic suggestions for the EMS 2010 annual meeting theme “Complex Systems in Biology and Risk Assessment.”

7:15 AM–7:40 AM

Biochemistry of Triple Helix Formation; Implications for Oligonucleotide Therapeutics
Zhanna Sobol (Pfizer Global R&D)

7:35 AM–8:00 AM

Toxicology Associated with Oligonucleotide Therapeutics
Husam Younis ( Isis Pharmaceuticals Inc.)

8:00AM–8:25 AM

What is an Appropriate Genetic Toxicological Endpoint Regarding Oligonucleotide Therapeutics?
Kevin Sweder (Bristol-Myers Squibb)

8:25 AM–8:30 AM

General Discussion and Concluding Remarks