EMS 2009 Annual Meeting

Sunday, October 25, 2009
7:00 AM–5:00 PM
	Registration

7:00 AM–8:30 AM
	Breakfast Meetings
	Heritable Mutation and Disease Special Interest Group	Leaders: Steve S. Sommer, MEDomics and Carole Yauk, Health Canada
	Epigenetics Special Interest Group	Leaders: Olga Kovalchuk, University of Lethbridge and Catherine B. Klein, New York University School of Medicine
	*Transgenic & In Vivo* Mutagenesis Special Interest Group**	Leaders: Kathleen A. Hill, The University of Western Ontario and Mugimane Manjanatha, National Center for Toxicological Research, U.S. FDA


8:30 AM–12:00 NOON
	Plenary Lecture 2 Past EMS Presidents Plenary Symposium	Chairpersons: Michael J. Plewa, University of Illinois at Urbana-Champaign and Priscilla K. Cooper, Lawrence Berkeley National Laboratory
8:30 AM–8:45 AM	Introduction
8:45 AM–9:15 AM	40 Years of Environmental Mutagenesis: What is it and What is it Good For? Speaker: David J. Brusick, Consultant
9:15 AM–9:45 AM	EMS and Government Scientists: A Symbiosis Speaker: David M. DeMarini, U.S. Environmental Protection Agency
9:45 AM–10:15 AM	Perspectives on DNA Repair as a Focal Point in the EMS Speaker: Philip Hanawalt, Stanford University
10:15 AM–10:30 AM	Break
10:30 AM–11:00 AM	Genomics in the Environmental Century: A Tribute to the EMS as a Society Speaker: Michael D. Waters, Integrated Laboratory Systems, Inc.
11:00 AM–11:30 AM	High Throughput Technologies: How they Drive New Conceptions of Productive Scientific Inquiry Speaker: Martina L. Veigl, Case Western Reserve University
11:30 AM– 12:00 NOON	Towards Understanding Differences Between Rodents and Humans in Cancer Susceptibility Speaker: Sheila M. Galloway, Merck Research Laboratories


12:00 NOON–1:30 PM
	Lunch on Own

12:30 PM–1:30 PM
	Committee Meetings
	2010 Program Committee (first meeting)	Chairperson: Jeffrey L. Schwartz, University of Washington
	Publication Policy Committee	Chairperson: Malcolm J. Lippert, Saint Michael's College and Stephen D. Dertinger, Litron Laboratories

1:30 PM–4:30 PM
	Symposium 1 Intrinsic Genomic Instability from Naturally Occurring DNA Structures Contributing Sponsor: Office of Rare Diseases, NIH	Chairpersons: Karen M. Vasquez, University of Texas MD Anderson Cancer Center and Joann B. Sweasy, Yale University School of Medicine
1:30 PM–1:34 PM	Introduction
1:34 PM–2:02 PM	Transcription and “Repair” in Non-B Form DNA Speaker: Philip C. Hanawalt, Stanford University
2:02 PM–2:30 PM	Non-B Form DNA and Mutagenesis Speaker: Karen M. Vasquez, UT MD Anderson Cancer Center
2:30 PM–2:45 PM	Methylation in CPG Repeats Can Alter Higher-Order DNA and Chromatin Structures and Cause Genetic Instability in Mammalian Cells Wang GW, Vasquez KV. Department of Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Smithville, TX, United States
2:45 PM–3:20 PM	Sequence Context-Dependent Polβ Mutators Identified in Human Tumors Speaker: Joann B. Sweasy, Yale University School of Medicine
3:20 PM–3:55 PM	Mechanisms of Induction of Multiple Mutations by DNA Polymerases Speaker: Jan Drake, National Institute of Environmental Health Sciences
3:55 PM–4:30 PM	Processing of Oxidative DNA Lesions Speaker: Susan S. Wallace, University of Vermont

1:30 PM–4:30 PM
	Symposium 2 Mutagenic Mode(s) of Action and Their Application in Cancer Risk Assessment Primary Sponsor: U.S. Environmental Protection Agency	Chairpersons: Nagu Keshava, U.S. Environmental Protection Agency and David A. Eastmond, University of California, Riverside
1:30 PM–1:45 PM	Introduction: Mutagenic Modes of Action in the Context of the U.S. Environmental Protection Agency’s Carcinogenic Risk Assessment Guidelines Speaker: Nagu Keshava, U.S. Environmental Protection Agency
1:45 PM–2:15 PM	Implications of DNA Adduct DosenResponse for Risk Assessment Speaker: Kenneth Turteltaub, Molecular Toxicology Group, Lawrence Livermore National Laboratory
2:15 PM–2:45 PM	Assessing In Vitro Dose-Response Relationships for Aneugens Speaker: David A. Eastmond, University of California, Riverside
2:45 PM–3:15 PM	Characterizing Dose Response Relationships to Inform Risk Decisions Speaker: Krista L. Dobo, Pfizer Inc.
3:15 PM–3:45 PM	Characterizing Multiple Modes of Carcinogenesis Using Toxicogenomic Methods Speaker: Michael D. Waters, Integrated Laboratory Systems, Inc.
3:45 PM–4:30 PM	Panel Discussion

1:30 PM–4:30 PM
	Symposium 3 The Next 50 Years of Research in Germ Cell Mutagenesis Contributing Sponsor: Office of Rare Diseases, NIH	Chairperson: Jack B. Bishop, National Institute of Environmental Health Sciences
1:30 PM–1:35 PM	Welcome and Introductions Speaker: Jack B. Bishop, National Institute of Environmental Health Sciences
1:35 PM–2:00 PM	The Next 50 Years in Germ Cell Mutagenesis Research? Speaker: Jack B. Bishop, National Institute of Environmental Health Sciences
2:00 PM–2:45 PM	Genome Resequencing for Germ-Cell Mutagenesis: Exploring the Full Range of Mutations Speaker: Matthew E. Hurles, Wellcome Trust Sanger Institute
2:45 PM–3:15 PM	Strategies in Looking for Mutations in Offspring of Cancer Survivors Speaker: John J. Mulvihill, University of Oklahoma Health Sciences Center
3:15 PM–3:45 PM	Can Regulatory Agencies Better Use Germ Cell Mutation Data? Speaker: Tim Singer, Health Canada
3:45 PM–4:30 PM	Panel Discussion: Where Do We Go From Here? Moderator: Andrew J. Wyrobek, Lawrence Berkeley National Laboratory Discussion Panelists: Christopher M. Somers, University of Regina, Rosalie K. Elespuru, U.S. Food and Drug Administration, Kerry L. Dearfield, U.S. Department of Agriculture, Steve S. Sommer, MEDomics, and Yuri E. Dubrova, University of Leicester

4:30 PM–6:30 PM
	Poster Session 1 and Exhibits Odd Numbered Abstracts Attended

6:30 PM–7:30 PM
	Committee Meetings
	Membership and Professional Development Committee	Chairpersons: Ofelia A. Olivero, National Cancer Institute, NIH and Kandace J. Williams, University of Toledo College of Medicine
	Finance Committee	Chairperson: Ronald D. Snyder, Schering-Plough Research Institute

7:30 PM–8:00 PM
	Special Interest Group Leaders Meeting