Morning Meetings

2008 Program Committe (second meeting)

Town Hall Meeting

High Mobility Group Protein B1 Enhances DNA Repair and Chromatin Modification Following DNA Damage
Lange S.S., Vasquez K.M.

Epigenetic Alterations in High and Low LET Radiation Induced Genomic Instability
Aypar U., Morgan W.F., Baulch J.E.

Epigenetic Mechanisms Underlie Estrogen- and Radiation-Induced Mammary Carcinogenesis
Kutanzi K., Koturbash I., Kovalchuk O.

Chemical Stressors in Fathers Alter Allele-Associated DNA Methylation of the 45S rRNA in Progeny
Anderson L.M., Ge X., Spurrier J.M., McCann S.D., Wang C., Crawford E.B., Fields J.R., Leighty R.M., Quinones O.A., Alvord W.G., Shiao Y.H.

BAX Splice Variant Expression Following Radiation Exposure in Human Lymphoblastoid Cells
Banda M., Thomas R.A., Tucker J.D.

Genome Organizer STAB1 in DNA Repair
Ayers S., Li J., Han H-J., Cai S., Kohwi-Shigematsu T.
(Previously in Symposium 16)

Functional Interaction of Human TDG with FMRP and XPG in Base Excision Repair of T/G Mismatches
Hang B., Budworth H., Sarker A.l., Cooper P.K.

Role of Chromatin Remodeling in DNA Repair, Cell Cycle Response, and Tumor Suppression
Venkatachalam S., Nagarajan P., Rajagopaln S., Samaan G., Onami T., Donnell R.

Topical Review 2
Repair of Ionizing Radiation-Induced DNA Double-Strand Breaks: Complex Pathways for Complex Lesions
Speaker: Susan Lees-Miller, University of Calgary

Plenary Lecture (PL4)
EMS Award Winner
Somatic Cell Genetics Fostered DNA Repair
Speaker: Larry H. Thompson, Lawrence Livermore National Laboratory

Lunch on Own

Symposium 14
Spontaneous and Oxidative Mutagenesis In Vivo

Recent Topics of Mutation Research with gpt delta Mice/Rats
Speaker: Takehiko Nohmi, National Institute of Health Sciences, Japan

Mutation Showers
Speaker: Steve S. Sommer, City of Hope

Prevention of Oxidative Mutagenesis by MYH: Implication in Human Cancer
Speaker: Teruhisa Tsuzuki, Kyushu University, Japan

Antioxidants Suppress Genetic Instability and Lymphoma in ATM Deficient Mice
Speaker: Robert Schiestl, University of California, Los Angeles

What ΦX174 Has Taught Us About the Spontaneous Mutation Frequency of Transgenic Mutation Targets
Speaker: Carrie R. Valentine, National Center for Toxicological Research, U.S. FDA

Symposium 15
Development of Novel, Rapid, and Portable Environmental Detection Methods

Primary Sponsor: U.S. Department of Homeland Security

Environmental Detection Strategy for Homeland Security
Speaker: Lance R. Brooks, Department of Homeland Security

Development of a Hand-Held Gas Chromatograph for Detection of Chemical Hazards
Speaker: Richard Kottenstette, Sandia National Laboratories

LISA Manportable: A RAMAN Based Stand-Off Chemical Detector
Speaker: Jeromy Rezac, ITT Industries

Rapid Multiplexed Nucleic Acid and Antibody Based Sensor for Microbial Detection
Speaker: Michael R. Meyer, ICx Technologies

Microbial Detection Using Single Molecule DNA Barcodes
Speaker: David Hoey, U.S. Genomics, Inc.

Symposium 16
Epigenetic Mechanisms, DNA Repair, and Chromatin

Primary Sponsor: Office of Science (BER), U.S. Department of Energy, Grant No. DE-FG02-08ER64662

Chairperson: Olga Kovalchuk, University of Lethbridge

Thymine DNA Glycosylase, DNA Base Excision Repair and (Epi)Genome Maintenance
Speaker: Primo Schär, University Basel, Switzerland

DNA Damage, Epigenetic Alterations and Liver Carcinogenesis
Speaker: Igor Pogribny, National Center for Toxicological Research, U.S. FDA

Cytosine Methylation in CpG Repeats Causes Genetic Instability by Affecting DNA and Chromatin Structures
Speaker: Karen M. Vasquez, UT MD Anderson Cancer Center
(Previously in Platform Session 3)

Persistent Genomic Instability: Memory of an Insult Requires DNA Methyltransferase I
Speaker: Bevin P. Engelward, Massachusetts Institute of Technology

Poly(ADP-ribosyl)ation Causes Rapid Chromatin Decondensation at Sites of Micro-IR-Induced Double-Strand Breaks
Speaker: Michael Hendzel, Cross Cancer Institute and University of Alberta

Platform Session 4
Environmental Exposures an Carcinogenic Risk

Abstracts 25–32

The Adaptive Response in Different Groups Occupationally Exposed to Ionizing Radiation and Chemicals
Vaglenov A., Parker D., Ernsthausen L., Marcos R., Creaus A., Simonian A.

TiO2 Nanoparticles Induce Genetic Instability and Oxidative Damage In Vivo in Mice
Trouiller B., Solaimani P., Reliene R., Schiestl R.

Biomarkers of Exposure and Effect in Migrant Farmworker Children of Mexican Origin From Urban and Agricultural Regions of Texas
Hernández-Valero M.A., Swank A.E., Winnik W.M., Abdel-Rahman S.Z., Jones L.A., DeMarini D.M.

Longterm Effects of First-Hand and Second-Hand Smoke on Sperm Function and DNA Integrity
Polyzos A., Gundel L., Destaillats H., Marchetti F.

Central Nervous System Expression of Troponin T 1 as a Biomarker of Neuropsychiatric Stress After Interferon-a, Ionizing Radiation and Ktamine Treatment
Lowe X., Marchetti F., Lu X., Wyrobek A.

Centrosomal Amplifications, a Genotoxic Mechanism Common to Nucleoside Analogs, could be inhibited by the Antioxidant WR 1065
Yu M., Olivero O.A., Poirier M.C.

Long-Term Exposure to Submicromolar Arsenite Induces Chromosome Instability Via Bypass of the Spindle Assembly Checkpoint in Mammalian Cells
Mauro M., Leszczynska J., Barbata G., Caradonna F., Sciandrello G., Rossman T.G., Klein C.B.

Moving Beyond Traditional Genetox Testing: Development of New Animal Alternative Genotoxicity Assays for Micronuclei and Comet in 3D Human Skin Models
Aardema M., Reisinger K., Corvi R., Curren R., Krul C., Pfuhler S., Ouedraogo G.

EMS Council Meeting