EMS 2011 Annual Meeting

Monday, October 17
7:00 AM–5:00 PM
	Registration	Inscription
7:00 AM–5:00 PM
	Speaker Ready Room Open	Inscription 2
7:00 AM– 8:30 AM
	Breakfast Meetings
	Breakfast Pick-Up for Meetings (Ticket Required—Breakfast Available at 6:45 AM)	Net Café
	DNA Repair and Mutagenic Mechanisms Special Interest Group Leaders: Mats Ljungman, The University of Michigan Medical School and Joann B. Sweasy, Yale University School of Medicine	Fontaine F
	Heritable Mutation and Disease Special Interest Group Leaders: Francesco Marchetti and Carole Yauk, Health Canada	Fontaine G
	Risk Assessment Special Interest Group Leaders: David A. Eastmond, University of California, Riverside and Nagu Keshava, U.S. Environmental Protection Agency	Fontaine H
8:30 AM–6:30 PM
	Posters and Exhibits Open	Fontaine B
8:30 AM–9:30 AM
	Plenary Lecture 2 (PL2) DNA Damage and Repair in Cancer: From Basic Science to Anti-Cancer Treatments Chairperson: Mats Ljungman, The University of Michigan Medical School Lecturer: Thomas Helleday, Gray Institute for Radiation Oncology and Biology	Outremont
9:45 AM–12:15 PM
	Symposium 5 Mechanisms and Roles of PARP in Response to Environmental Genotoxins Chairpersons: Robert W. Sobol, Jr., University of Pittsburgh Cancer Institute and Guy G. Poirier, Laval University Organized by the DNA Repair and Mutagenic Mechanisms Special Interest Group Supported in part by: Trevigen, Inc.	Mont-Royal
9:45 AM–10:05 AM	Programming of DNA Damage Signaling and Repair by Poly(ADP-ribose) Guy Poirier, Laval University
10:05 AM–10:25 AM	Targeted Therapy of Breast Cancer Using PARP Inhibitors James M. Ford, Stanford University
10:25 AM–10:45 AM	NAD⁺-Dependent Gene Regulation by PARP-1 W. Lee Kraus, University of Texas Southwestern Medical Center at Dallas
10:45 AM–11:00 AM	Break—In the Exhibit Hall
11:00 AM–11:20 AM	Analysis of the NAD Metabolome in Response to DNA Alkylation Charles Brenner, University of Iowa
11:20 AM–11:40 AM	Role of PARP Inhibitors in ATM Deficient Human Malignancies Susan Lees-Miller, University of Calgary
11:40 AM–12:00 NOON	Temporal and Spatial Resolution of PARP Activation-Induced Cellular Energy Modulation Robert W. Sobol, Jr., University of Pittsburgh Cancer Institute
12:00 NOON–12:15 PM	Discussion
9:45 AM–12:15 PM
	Symposium 6 Environmental Exposures’ Impact on Male Germ Cells and Consequences to the Embryo: Is the Predominant Damage Genetic/Epigenetic? Chairpersons: Francesco Marchetti, Health Canada and Bernard Robaire, McGill University Organized by the Heritable Mutations Special Interest Group	Outremont
9:45 AM–10:15 AM	Impact of Paternal Drug Exposures on Progeny Outcome: The Roles of Genetic versus Epigenetic Mechanisms Barbara F. Hales, McGill University
10:15 AM–10:45 AM	Role of Histone Modifications in Male Germ Cell Development and Progeny Outcome Sarah Kimmins, McGill University
10:45 AM–11:00 AM	Break—In the Exhibit Hall
11:00 AM–11:30 AM	Effects of Dietary Folic Acid Intake on Germ Cells within and across Generations Michael G. Wade, Health Canada
11:30 AM–12:00 NOON	Environmental Organochlorine Exposures and Sex Chromosome Disomy in Human Sperm Melissa J. Perry, The George Washington University
12:00 NOON–12:15 PM	Discussion
12:15 PM–2:00 PM
	Lunch on you own
12:15 PM–12:30 PM
	Boxed Lunch Pick-Up (For EMS Business Meeting and Town Hall)	Outremont Foyer
12:30 PM–1:45 PM
	EMS Business Meeting and Town Hall (Boxed Lunches Available)	Outremont
2:00 PM–4:30 PM
	Symposium 7 Application of Epigenetics and Epigenomics Approaches in the Investigation of Human Disease Chairpersons: Jennifer C. Sasaki, Alkermes, Inc. and Sundaresan Venkatachalam, National Institute of Dental and Craniofacial, NIH Organized by the New Technologies Special Interest Group	Mont-Royal
2:00 PM–2:15 PM	Introduction Sundaresan Venkatachalam, National Institute of Dental and Craniofacial, NIH
2:15 PM–2:45 PM	Coordination of Regulation of DNMT1 Stability W. David Sedwick, Case Western Reserve University
2:45 PM–3:15 PM	Translating Epigenetic Biology into Novel Treatments for Cancer Owen A. O’Connor, NYU Langone Medical Center
3:15 PM–3:30 PM	Break—In the Exhibit Hall
3:30 PM–4:00 PM	Epigenetic Epidemiology: Examples from Alzheimer’s Disease Laura S. Rozek, University of Michigan
4:00 PM–4:30 PM	Emerging Science and Technologies to Explore Epigenetic Mechanisms: Better Understanding of Human Diseases Winnie Wan-yee Tang, Johns Hopkins Bloomberg School of Public Health
2:00 PM–4:30 PM
	Symposium 8 Site of Contact and Systemic Effects of Formaldehyde Exposure Chairpersons: Luoping Zhang, University of California, Berkeley and James Swenberg, University of North Carolina Contributing Sponsor: National Institute of Environmental Health Sciences	Outremont
2:00 PM–2:05 PM	Introduction Luoping Zhang, University of California, Berkeley
2:05 PM–2:30 PM	Evaluation of Formaldehyde As a Potential Cause of Human Leukemia Bernie Goldstein, University of Pittsburgh
2:30 PM–2:55 PM	Detection of Formaldehyde-Induced Bone Marrow Toxicity and Allergic Asthma in Experimental Animal Models Xu Yang, Central China (Huazhong) Normal University
2:55 PM–3:20 PM	Potential Genetic and Epigenetic Effects of Formaldehyde James Swenberg, University of North Carolina
3:20 PM–3:35 PM	Break—In the Exhibit Hall
3:35 PM–4:00 PM	Reproductive and Developmental Toxicity of Formaldehyde: A Systematic Review Luoping Zhang, University of California, Berkeley
4:00 PM–4:30 PM	Discussion
2:00 PM–4:30 PM
	Platform Session 1 DNA Repair Chairpersons: Bevin P. Engelward, Massachusetts Institute of Technology and Kendace J. Williams, University of Toledo College of Medicine Presenting author is underlined.	Verdun
2:00 PM–2:15 PM	Oligonucleotide Retrieval: A Versatile Technology for Calibrating the Fidelity of DNA Synthetic Processes In Vivo Shen JC¹, Fox EJ¹, Loeb LA¹ ². ¹Department of Pathology, University of Washington, Seattle, WA, United States, ²Department of Biochemistry, University of Washington, Seattle, WA, United States
2:15 PM–2:30 PM	Comet-Fish to Sensitively Assess Global and Transcription-Coupled Repair of DNA Lesions Spivak G, Guo J, Hanawalt PC. Stanford University, Stanford, CA, United States
2:30 PM–2:45 PM	Chemotherapeutic Alkylation Treatment: Tumor Cell Response Kim S, Williams KJ. University of Toledo College of Medicine, Toledo, OH, United States
2:45 PM–3:00 PM	Alkylation Sensitivity Screens Reveal a Cross-Species Functionome Svilar D¹, Brown A¹, Tang JB¹, McDonald PR¹, Shun TY¹, Wang XH¹, Lazo JS¹, Begley TJ², Sobol RW¹. ¹University of Pittsburgh, Pittsburgh, PA, United States, ²University at Albany, State University of New York, Rensselaer, NY, United States
3:00 PM–3:15 PM	Structure and Substrate Specificity of a Mouse NEIL3 Ortholog Liu M¹, Imamura K¹, Averill A¹, Jaruga P², Zhao X³, Burrows CJ³, Dizdaroglu M², Doublié S¹, Wallace SS¹. ¹Department of Microbiology and Molecular Genetics, The Markey Center for Molecular Genetics, University of Vermont, Burlington, VT, United States, ²Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD, United States, ³Department of Chemistry, University of Utah, Salt Lake City, UT, United States
3:15 PM–3:30 PM	Break—In the Exhibit Hall
3:30 PM–3:45 PM	Sumoylation of Ntg1 and the Regulation of Base Excision Repair in Saccharomyces cerevisiae Swartzlander DB¹, Powers HR¹, Corbett AH¹, Doetsch PW¹ ². ¹Emory University, Department of Biochemistry, Atlanta, GA, United States, ²Winship Cancer Institute, Atlanta, GA, United States
3:45 PM–4:00 PM	Radiation Mitigators Yel1 and Yel2 Inhibit Radiation-Induced Error-Prone Microhomology-Mediated Recombination Scuric Z¹, Farabi N¹, Schiestl RH¹. ¹David Geffen School of Medicine at UCLA, Los Angeles, CA, United States
4:00 PM–4:15 PM	FANCJ Functions in Error-Free UV DNA Repair Guillemette SS¹, Peng M¹, Cantor SB². ¹University of Massachusetts Medical School, Worcester, MA, United States
4:15 PM–4:30 PM	Unified Model for Fanconi Anemia and Breast Cancer Gene-Network in Protecting Stalled DNA Replication Forks Schlacher K¹ ², Jasin M¹. ¹Memorial Sloan-Kettering Cancer Center, New York, NY, United States, ²University of California, Los Angeles, Los Angeles, CA, United States
4:30 PM–6:30 PM
	Poster Session 2 and Exhibits Even Numbered Abstracts Attended	Fontaine B
6:30 PM
	Committee Meetings
	Alexander Hollaender Outreach Committee	Fundy
	Awards and Honors Committee	Longueuil
	Education, Student and New Investigator Affairs Committee	Pointe Aux Trembles
	Finance and Resource Committee	Jaques Cartier