Poster Session III (presenting author is in italics)

DNA Damage and Repair

P3
Role of Single Stranded Break Repair and XRCC1 in Neurodegeneration
Kulkarni A, Mcneill D, Wilson III D

P6
Xanthine DNA Glycosylase Activity from Mismatch-specific Uracil DNA Glycosylase (MUG)
Lee H-W, Wright C, Cao W

P9
Novel Xanthine DNA Glycosylase (XDG) Activities in Mammalian and Yeast Systems
Dong L, Glass RA, Meira LB, Samson LD, Cao W

P12
Xanthine DNA Glycosylase Activity in SMUG1 DNA Glycosylase from Geobacter Metallireducens
Mi R, Cao W

P15
The Role of Common Base Excision Repair Variants in Cancer Susceptibility
Yamtich J, Speed WC, Straka E, Kidd K, Sweasy JB

P18
Endonuclease V-Mediated Deamination DNA Repair: From Single-Molecule Study to Mammalian Systems
Cao W

P21
Post-Translational Modification of Enzymes Involved in Repair of Oxidative DNA Damage in Saccharomyces cerevisiae
Griffiths LM, Swartzlander D, Doetsch PW

P24
DNA Damage Causes Oxidative Stress in Saccharomyces cerevisiae?
Rowe LA, Hopkins M, Degtyareva NP, Doetsch PW

P27
Tumor-Associated Variants of DNA Polymerase ß and a Functional Link to Cancer Etiology
Donigan KA, Sweasy JB

P29
Unnatural Substrates Reveal the Importance of 8-oxoG for In Vivo Mismatch Recognition and Repair by MutY Glycosylase
Livingston AL, O'Shea VL, Kim T, Kool ET, David SS

P31
Application of Protein Footprinting, Crosslinking, and Mass Spectrometry in Mapping Ape1 Contacts During BER Progression
Yu ET, Gaucher SP, Sale K, Young MM, Hadi MZ

P33
The Acetaldehyde-Derived Adduct N2-Ethyl-2’-deoxyguanosine Blocks RNA Pol II at the Extension Step, and T7 RNA Polymerase at the Insertion Step
Cheng T-F, Brooks PJ

P35
Expression of p53 Regulated Genes in Fanconi Anemia Cells After Mitomycin C and Hydroxyurea Exposure
Martinez A, Hinz J, Gomez-Laguna L, Molina B, Acuna H, Frias S, Coleman M

Mutagenesis, Carcinogenesis

P50
Comparative Investigations on the Genotoxicity Profile of Glutaraldehyde and Formaldehyde – What Makes the Difference?
Speit G, Neuss S, Schuetz P, Schmid O

P53
Frequency of Micronucleated Erythrocytes in the Peripheral Blood of Juvenile Male Rhesus Monkeys, Macaca Mulatta, Determined by Flow Cytometry
Myers M, Bishop M, Hotchkiss C, Lin C-J, Chen J, Mattison D, Morris S

P56
Development of a Method for Measuring Pig-a Gene Mutants in Rat Lymphocytes  Using Selection with Proaerolysin
Miura D, Dobrovolsky V, Mei N, Kasahara Y, Katsuura Y, Heflich R

P59
EU Cosmetics Association’s (COLIPA) Project on Development of Genotoxicity Testing in 3D Human Skin Models
Aardema MJ, Reisinger K, Ouedraogo G, Curren R, Krul CAM, Corve R, Pfuhler S

P62
Detection of Mutant Tumor Cancer Biomarkers by BEAMing
Karakas B, Elespuru RK, Weaver J, Diehl F, Park BH

P65
Validation of In Vitro Micronucleus Study in Human Lymphocytes
Farabaugh CS, Middendorf CA, Leatherberry RS, Escobar MM, Stankowski Jr LF

P68
Further Development and Validation of the In Vitro Micronucleus Assay in the EpiDermTM 3D Reconstructed Human Skin Model
Hu T, Mun GC, Kaluzhny Y, Hayden P, Barnett B, Wilt N, Klausner M, Curren RD, Aardema MJ

P71
ECVAM Retrospective Validation of the  Micronucleus Test In Vitro
Corvi R, Albertini S, Hartung T, Hoffmann S, Maurici D, Pfuhler S, van Benthem,J, Vanparys P

P74
Conditions Affecting Mutation Frequency in the Mouse Lymphoma Forward Mutation Assay
Sahm J, Luo FQ

P77
An In Vitro Alternative System for Genotoxic Screening of Compounds
Mahabir AG, Schaap MM, Hendriksen CFM, van Steeg H, van Benthem J

P83
Bhas Cell Transformation Assay as a Predictor of Carcinogenicity
Poth A, Kunz S, Heppenheimer A

P86
Novel In Vivo Mutation Assay Based on the Endogenous Pig-A Locus
Bryce S, Bemis J, Dertinger S

P89
Experience With a Combined In Vivo Micronucleus and Comet Assay Test Protocol in Mice and Rats
Recio L, Hobbs-Riter C, Shephard K, Baldetti C, Winters J, Caspary W, Tice R, Witt K

P91
Microindels Due to Highly Error-Prone Processes
Sommer SS, Ki K, Gu D, Gonzalez KD, Hill KA, Scaringe WA

P93
Chemical Induced Bystander Effect: Evidence and Significance
Asur R, Thomas RA, Tucker JD

P95
Reoxygenation Following Hypoxia Activates DNA-damage Checkpoint Signaling Pathways that Suppress Cell Cycle Progression in Cultured Human Lymphocytes
Kim BM, Choi JY, Kim YJ, Woo HD

P97
Gene Polymorphism and the Risk of Cutaneous Malignant Melanoma in Brazil
Toledo Gonçalves F RP, Souza S, Eluf Neto J, Kohler P, Gattás GJF

P99
A Role for Thymine Nucleotide Insufficiency in Breast Carcinogenesis?
Barclay BJ, Murray D

P101
Pathogenic Mutations in PEO1 Cause Biochemical Defects in the Human Mitochondrial DNA Helicase
Longley MJ, Sharief FS, Copeland WC

Genotoxins, Mutagens, Antimutagens, Biodosimetry, Risk Assessment

P105
Antimutagenic Effects of Caffeic Acid Phenethyl Ester (CAPE) in Human Breast Cancer Cells and Relationship to Gene Expression
Lyon JL, Leszczynska JM, Wu J, Frenkel K, Klein CB

P108
Recent Advances Using the CD71 Based Flow Cytometric Micronucleus Analysis Method
Torous D, Bishop J, Fiedler R, Heflich R, Krsmanovic L, MacGregor J, Recio L, Dertinger S

P111
The Effect of Age on Xenobiotic Metabolizing Enzyme Activity in Rat Liver Microsomes
Mills C, DeVito MJ

P114
Assessment of Mutagenicity in Hairdressers by Cytogenetic Tests
Galiotte MP, Kohler P, Mussi G, Gattás GJF

P117
Independent Validation of the GreenScreen HC GADD45α-GFP Genotoxicity Assay Using Fifty Proprietary and Non-Proprietary Compounds
Olaharski AJ, Kirchner S, Uppal H, Kolaja K

P120
Human Biomonitoring Studies in the Indian Population Using the Alkaline Comet Assay
Dhawan Al, Bajpayee M, Pandey A, Parmar D

P123
Failure of Antimony Trioxide to Induce Micronuclei or Chromosomal Aberrations in Rat Bone Marrow after Sub-Chronic Oral Dosing
Kirkland D, Whitwell J, Deyo J, Serex T

P126
Genomic Instability in Show Workers Modulated by Polyvitamin-Polymineral Treatment. Evaluation of Therapeutic Effect Before and After 4 Months 2 Tablets  Daily Intake of Centrum Using Pancentromeric FISH
Vaglenov A, Lalchev S, Marcos R, Creus A

P129
Interaction between Bleomycin and Aminoacridines in an Assay for Mutagenic and Recombinagenic Effects in Yeast
Hoffmann GR, Ronan MV, Sylvia KE, Tartaglione JP

P132
Genotoxicity of Polymeric Gene Carrier, Polyethylenimine (PEI) and Polyamidoamine (PAMAM) Dendrimer, in Human Blood Lymphocytes determined by Single Cell Gel Electrophoresis and Micronucleus Assay
Choi YJ, Kang SJ, Jeon HK, Kim YJ, Chung HW

P135
Effects of Co-Exposure to Electromagnetic Fields and Clastogens on DNA Damage Determined by the Alkaline Comet Assay and Chromosomal Aberration Test
Lee M, Kim J-Y

P138
Evaluation of Kava Extracts and Kavalactone Standards for Mutagenicity and Toxicity
Whittaker P, Clarke J, Dunkel V, Jaeger L, Seifried H, Betz J, San R

P141
Identification of Persistent Gene Expression BioSignatures for Acute Radiation Exposure
Kulkarni R, Thomas RA, Tucker JD

P144
Genotoxicity and Apoptosis Induced by Hydroquinone and Benzoquinone in HL-60 and Jurkat Cells
Kim YJ, Choi JY, Woo HD, Choi YJ, Kang SJ, Chung HW