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Poster Assignments

Poster Session II

Mutational and Epigenetic Mechanisms of Susceptibility and Risks for Genetic Diseases

(information subject to change)

| Poster Session I 4:45 PM–7:00 PM | Poster Session II4:45 PM–7:00 PM | Poster Session III 12:00 Noon–2:00 PM |

Monday, October 22, 2007
4:45 PM–7:00 PM

Poster Session II (presenting author is in italics)

 

DNA Damage and Repair

P2
The Tp53 Gene is a Key Regulator of the Radioadaptive Response for DNA Damage In Vivo
Schmid TE, Marchetti F, Polyzos A, Bhatnagar S, Wyrobek AJ

P5
Screening Mycobacterium Tuberculosis Genome for Genes Involved in Cellular Response to Nitrosative Stress
Park S-H, Hart L, Cao W

P8
Human DNA polymerase nu (POLN): residues important for its low fidelity and bypass activity
Takata KT, Wood RD

P11
Genetic Characterization of the Role of Bacterial DNA Mismatch Repair in Sodium Nitrite Mutagenesis
Deschenes SM

P14
The Relation Between DNA Damage and Hyperglycemia in KK-Ay Mice
Hashimoto K, Takasaki W, Yamoto, T, Manabe S, Sato,I, Tsuda S

P17
Influence of Polymorphisms in DNA Repair Genes on the Initial Repair of MMS-Induced DNA Damage, as Measured by the Comet Assay
Ryk C, Routledge MN, Allan JM, Wild CP, Kumar R, Lambert B, Hou S

P20
Profiling Key Phospho-Protein Kinetics in Different Cell Types After Low and High LET Exposure
Whalen MK, Gurai SK, Pluth JM

P23
Post-Translational Phosphorylation of hMSH6 and Mismatch Recognition Activity
Kaliyaperumal S, Williams K

P26
Association Between Gene Polymorphisms and the DNA Repair Capacity in Young Lung Cancer Patients
Roessler U, Rosenberger A, Sauter W, Bickeboeller H, Illig T, Wichmann HE, Hornhardt S, Gomolka M

P28
Factors Affecting DNA Repair Gene Expression Levels: Impact on the Use of mRNA Expression to Predict Acute Side Effects of Radiotherapy
Popanda O, Woelfelschneider A, Lilla C, Mayer C, Debus J, Bartsch H, Chang-Claude J, Schmezer P

P30
Analysis of Chromosomal Structural Damage in Lymphocytes and Sperm From Hodkin’s Disease Patients Treated With MOPP/ABVD(P) Chemotherapy With or Without Radiotherapy
Frias Vazquez S, Salas C, Lopez de Lara O, Olivares JJ, Molina B, Niembro A, Lozano V, Rivera Luna R, Carnevale A

P32
Genetic Analysis of DNA Strand Break Repair and Loss of Heterozygosity in p53 Deficient and Wildtype Hematopoietic Stem Cells Shows Haplotype Dependent Efficiency of Repair
French JE, Parron VI

P34
The Effect of DNA Ethylation on RNA Polymerase II Transcription in the Yeast Saccharomyces cerevisiae
Shaheen Z, Bouska C, Ward K, Reagan M

P36
A High Resolution Oligonucleotide CpG Island Microarry
Foo C, Hopkins C, Roberts D

Epigenetics, Germ Cells

P38
Micro-RNA Regulation of Stroke Recovery
Lowings MD, Kolb B, Kovalchuk O

P40
Cytosine Methylation in CG Repeats Increases Local Genetic Instability
Wang G, Vasquez K

P42
miRNA Regulation in Human Bystander Tissue Suggests Common Bystander Regulatory Elements
Zemp FJ, Sedelnikova OA, Bonner WM, Kovalchuk O

P44
Synergistic Effects of Estrogen and Ionizing Radiation on the Epigenetic Processes in the Rat Mammary Gland
Kutanzi KR, Koturbash I, Kovalchuk O

P46
Evidence for Promoter Methylation Effects on Proximal Splicing of MLH1 mRNA in Colon Cancer Cell Lines
Tiedtke E, Sedwick DW, Skandalis A

P47
Genetic Dissection of Susceptibiligy/Resistance to Ionizing Radiation by use of Recombinant Congenic Strain Mice
Vaglenov A, Kaltenboeck B, Brawner W, Carpenter D, Fortin A, Brandhorst H, Yihang L

Mutagenesis, Carcinogenesis

P49
Genes Involved in Inflammatory Responses Following Exposure to Cigarette Smoke in Normal Human Bronchial Epithelial (NHBE) Cells
Parsanejad R, Fields W, Steichen T, Bombick B, Doolittle D

P51
8OG Can Lead to Ras Activation in a Mammalian Model of Transcriptional Mutagenesis
Saxowsky TT, Doetsch PW

P54
Mechanistic Investigation of a Test Article-Induced Increase in Mitotic Index in the HPBL Chromosome Aberration Assay
Mahadevan B, Nioi P, Mack M, Martin B, Sullivan E, Snyder R

P57
ACB-PCR Measurement of K-Ras Codon 12 Mutation in A/J Mouse Lung Exposed to Benzo[a]pyrene: A Dose-Response Assessment
Meng F, Knapp G, Green T, Ross J, Parsons B

P60
The Relative Ability of Cannabis and Tobacco Smoke to Induce Chromosomal Damage in Murine Pulmonary Cells
Maertens RM, White PA, Rickert W, Levasseur G, Dougals GR, Desjardins S

P63
Chronic Oxidative DNA Damage Causes Chromosome Instability in Yeast Saccharomyces cerevisiae
Degtyareva N, Cheng L, Mieczkowski P, Doetsch P

P66
Major DNA Repair Pathways Influencing Transcriptional Mutagenesis in Escherichia coli
Clauson CL, Weiss B, Doetsch PW

P69
DUN1-Mediated Pathway That Controls Ribonucleotide Reductase Induction is Required for Both Aflatoxin B1 (AFB1)-Associated Sister Chromatid Exchange (SCE) and Mutation in Saccharomyces cerevisiae (Yeast)
Fasullo MT, Sun M, Egner P

P72
Mutagenicity and Loss of Heterozygosity (LOH) of Microsatellites Markers in Chromosome 11b of Mouse Lymphoma Cells Treated With Taxol
Schisler MR, Wood AJ, Geter DR, Gollapudi BB, Seidel SD

P75
Mitochondrial DNA Sequence Variants in Mice Treated Transplacentally with AZT
Kunugita N, Mittelstaedt RA, Von Tungeln LS, Beland FA, Heflich RH

P78
Regulation of Saccharomyces cerevisiae DNA Polymerase eta transcript and protein
Pabla R, Rozario D, Siede W

P80
The Newly Defined Acceptance and Evaluation Criteria for the Mouse Lymphoma Assay and Their Impact and Relevance
Poth A, Kunz S, Wollny E

P81
Abasic Sites are Strong Blocks to Multisubunit RNA Polymerases at the Incorporation and Extension Steps, and Incorporation Follows the “A-rule”
Cheng TF, Brooks PJ

P84
Genotoxicological and Ecotoxicological Evaluation of Cyanobacterial Strains using Plant and Fish Bioassays
Laughinghouse IV HD, Prá D, Rieger A, Silva-Stenico ME, Fiore MF, Franke SIR

P87
Spontaneous Mutation Frequencies in Spleen in the lacI and FX174 Transgenic Mouse Mutation Assays
Valentine CR, Rainey HF, Farrell JM, Shaddock JG, Dobrovolsky VN, Delongchamp RR

Genotoxins, Mutagens, Antimutagens, Biodosimetry, Risk Assessment

P104
Contamination With Tritium Induced Genetic Instability
Saintigny Y, Lopez BS

P107
Evaluation of Genotoxic Potential of Radiofrequency Electromagnetic Field (RF-EMF) in Duckweed
Cvjetko P, Radic S, Malaric K, Tkalec M, Pavlica M

P110
Correlation Studies Between Growth Processes in Plants and Genetic Endpoints in Mice Bone Marrow Cells
Patlolla BP, Sekhon BS

P113
Multi-Laboratory Evaluation of an Automated, High Content In Vitro Micronucleus Assay
Dertinger S, Bryce S, Avlasevich S, Bemis J, De Boeck M, Van Goethem F, Beerens D, Aerts H, Collins J, Ellis P, White A, Harvey J, Rees R, Lynch A, Lukamowicz M, Elhajouji,A

P116
Mechanisms Underlying Prevention of Genomic Instability in Breast Tumor Cells by Genistein and Lycopene
Batoon AK, Leszczynska J, Klein CB

P119
Dose-Response and Apparent Thresholds for DNA Adducts and Cytogenetic Effects in Rats Treated With MMS
Pottenger LH, Zhang F, Schisler MR, Charles GD, Wiescinski CM, Bartels MJ, Gollapudi BB

P122
Biological Monitoring and DNA Damage Evaluation of Occupational Exposure to Organic Solvents
Groot H, Narváez DM, Ortiz S, Rodríguez AF, Torres C, Varona M

P125
Association of DNA Damage and the Polymorphisms of the Enzymes CYP2E1, GSTM1 and GSTT1 in a Population Exposed to Organic Solvents
Groot H, Rodríguez AF, Ortiz S, Narváez DM, Torres C, Varona M

P128
REV1 Inhibition Reduces the Incidence of Carcinogen-Induced Murine Lung Tumors
Dumstorf CD, Mukhopadhyay SM, Zacharias WZ, McGregor WM

P131
Evaluation of Cytotoxicity Indicators for an In Vitro Alkaline Comet Assay in Primary Rat Hepatocytes: Utility in Avoiding False Positive Results
Gill S, Gealy R, Barnum J, Kraynak A, Storer R, Galloway S

P134
Detection of Mutagens Derived From 3,3’-Dichlorobenzidine in River Water Flowing Through an Industrial Area in Wakayama, Japan
Ohe T, Watanabe T, Hasei T, Wakabayashi K

P137
Environmental Effects on the Quality of Microarray Gene Expression Measurements
Fuscoe JC, Han T, Melvin CD, Desai VG, Moland CL, Scully AT

P140
In Vitro Micronucleus and Sister Chromatid Exchange Analyses in Chinese Hamster Ovary Cells Following Exposure to Whole Cigarette Smoke
Fowler KW, Harger KM, Morgan WT, Bombick BR, Doolittle DJ

P143
Identification of Novel TP53 Regulated Genes Induced by Ionizing Radiation
Bourguet F, Krefft A, Peterson LE, Coleman MA